ANALYSIS TYPE / 10
Light Propagation · Absorption · Scattering · Dosimetry
Overview
Tissue modelling simulates light absorption, scattering, and fluorescence in biological materials — enabling the design of medical devices, PDT systems, OCT instruments, and surgical lasers with accurate dosimetry predictions. Monte Carlo photon transport through layered tissue with wavelength-dependent optical properties predicts the treatment volume for PDT and the signal depth profile for OCT — enabling device design optimisation without animal studies.
Industries Served
Deliverables
Key Aspects
Simulating the statistical path of photons through turbid biological tissue using Monte Carlo methods — computing fluence rate distribution and absorbed energy density.
Specifying tissue optical properties — absorption coefficient, scattering coefficient, anisotropy factor, and refractive index — as a function of wavelength from published literature or measurement data.
Computing the photodynamic therapy light dose distribution in tissue — predicting the treatment volume and ablation boundary for a given source geometry and irradiance level.
Simulating the optical coherence tomography signal from layered biological tissue — predicting penetration depth, signal-to-noise ratio, and sensitivity roll-off with depth.
Connect with our optics & photonics simulation team to discuss the right approach for your application.
